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Direk Limmathurotsakul Selected Research

Melioidosis

12/2021A Comparison Between 12 Versus 20 Weeks of Trimethoprim-sulfamethoxazole as Oral Eradication Treatment for Melioidosis: An Open-label, Pragmatic, Multicenter, Non-inferiority, Randomized Controlled Trial.
11/2021Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis.
1/2021Role of Burkholderia pseudomallei-Specific IgG2 in Adults with Acute Melioidosis, Thailand.
1/2021Effectiveness of a multifaceted prevention programme for melioidosis in diabetics (PREMEL): A stepped-wedge cluster-randomised controlled trial.
1/2021A 2-Biomarker Model Augments Clinical Prediction of Mortality in Melioidosis.
1/2020Lactoferrin is a dynamic protein in human melioidosis and is a TLR4-dependent driver of TNF-α release in Burkholderia thailandensis infection in vitro.
1/2020Survival of Burkholderia pseudomallei and Pathogenic Leptospira in Cola, Beer, Energy Drinks, and Sports Drinks.
1/2020Serum From Melioidosis Survivors Diminished Intracellular Burkholderia pseudomallei Growth in Macrophages: A Brief Research Report.
1/2019Pan-drug-resistant and biofilm-producing strain of Burkholderia pseudomallei: first report of melioidosis from a diabetic patient in Yogyakarta, Indonesia [Letter].
1/2019Global burden of melioidosis in 2015: a systematic review and data synthesis.
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Direk Limmathurotsakul Research Topics

Disease

60Melioidosis
12/2021 - 05/2005
22Infections
10/2021 - 10/2005
13Sepsis (Septicemia)
01/2021 - 06/2007
4Leptospirosis
01/2020 - 01/2011
3Bacteremia
11/2021 - 05/2005
3Cryptococcal Meningitis
12/2015 - 03/2009
2Communicable Diseases (Infectious Diseases)
01/2021 - 01/2015
2Cross Infection (Nosocomial Infection)
01/2020 - 01/2019
2Neoplasms (Cancer)
01/2019 - 01/2018
2Neutropenia
01/2018 - 12/2015
2Scrub Typhus (Typhus, Scrub)
01/2016 - 01/2015
2Anemia
12/2015 - 03/2014
2Drug-Related Side Effects and Adverse Reactions
03/2014 - 10/2005
2Chronic Disease (Chronic Diseases)
01/2014 - 01/2013
1Chronic Renal Insufficiency
01/2021
1Pneumonia (Pneumonitis)
01/2021
1Ventilator-Associated Pneumonia
01/2021
1Inflammation (Inflammations)
01/2020
1Respiratory Insufficiency (Respiratory Failure)
01/2019
1Fever (Fevers)
01/2019
1Shock
01/2019
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2018
1Hypotension (Low Blood Pressure)
01/2018
1Digestive System Diseases
01/2018
1Persistent Infection
01/2018
1Infectious Arthritis (Septic Arthritis)
12/2017
1Hypokalemia
12/2015
1Alcoholism (Alcohol Abuse)
10/2015
1Glanders
06/2014
1Immune Reconstitution Inflammatory Syndrome
03/2014
1Body Weight (Weight, Body)
03/2014

Drug/Important Bio-Agent (IBA)

14Anti-Bacterial Agents (Antibiotics)IBA
11/2021 - 05/2005
9AntigensIBA
11/2021 - 09/2005
9AntibodiesIBA
11/2021 - 09/2005
8Proteins (Proteins, Gene)FDA Link
11/2021 - 01/2008
8VaccinesIBA
01/2021 - 01/2012
7EnzymesIBA
11/2021 - 01/2007
7ImmunosorbentsIBA
11/2021 - 01/2007
7Pharmaceutical PreparationsIBA
10/2021 - 10/2005
7Ceftazidime (Fortum)FDA LinkGeneric
12/2017 - 10/2005
5Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
12/2021 - 06/2005
4Immunoglobulin M (IgM)IBA
01/2016 - 03/2012
3Polysaccharides (Glycans)IBA
11/2021 - 01/2009
3Interleukin-10 (Interleukin 10)IBA
01/2021 - 04/2013
3Immunoglobulin G (IgG)IBA
01/2021 - 01/2013
316S Ribosomal RNAIBA
08/2012 - 11/2007
2Hemolysin Proteins (Hemolysins)IBA
11/2021 - 01/2018
2InterferonsIBA
01/2021 - 01/2013
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2021 - 08/2007
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2020
2Drinking WaterIBA
01/2020 - 02/2014
2IronIBA
01/2020 - 02/2007
2CytokinesIBA
01/2020 - 06/2007
2VancomycinFDA LinkGeneric
01/2019 - 01/2009
2FlagellinIBA
05/2017 - 09/2014
2Meropenem (Merrem)FDA LinkGeneric
06/2015 - 01/2012
2Biological Warfare AgentsIBA
06/2015 - 06/2014
2Amphotericin B (Amphotericin)FDA LinkGeneric
03/2014 - 03/2009
2Doxycycline (Periostat)FDA LinkGeneric
03/2014 - 10/2005
2Fusidic Acid (Fucithalmic)IBA
01/2013 - 01/2009
2Amoxicillin (Wymox)FDA LinkGeneric
01/2012 - 02/2008
2LactamsIBA
01/2012 - 10/2011
2Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
01/2012 - 02/2008
2Interferon-gamma (Interferon, gamma)IBA
10/2010 - 09/2009
2Messenger RNA (mRNA)IBA
07/2007 - 06/2007
1insulin receptor-related receptor (IRR)IBA
01/2021
1Interleukin-8 (Interleukin 8)IBA
01/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
01/2021
1Interleukin-17 (Interleukin 17)IBA
01/2021
1Colistin (Coly-Mycin)FDA Link
01/2020
1LactoferrinIBA
01/2020
1Drug CombinationsIBA
01/2020
1Glycoproteins (Glycoprotein)IBA
01/2020
1Guanosine Diphosphate (GDP)IBA
01/2019
1WastewaterIBA
01/2019
1Virulence Factors (Pathogenicity Factors)IBA
01/2018
1Lipid AIBA
01/2018
1Adrenergic Agents (Adrenergic Drugs)IBA
01/2018
1Lactic Acid (Lactate)FDA LinkGeneric
01/2018
1Nonsense Codon (Nonsense Mutation)IBA
05/2017
1Combined VaccinesIBA
01/2017
1Flucytosine (Ancobon)FDA Link
12/2015
1deoxycholate drug combination amphotericin BIBA
12/2015
1ElectrolytesIBA
12/2015
1CreatinineIBA
12/2015
1LatexIBA
09/2015
1Type VI Secretion SystemsIBA
02/2015
1Dihydrotachysterol (AT 10)IBA
03/2014
1Hemoglobins (Hemoglobin)IBA
03/2014

Therapy/Procedure

16Therapeutics
01/2021 - 10/2005
2Critical Care (Surgical Intensive Care)
01/2021 - 01/2019
1Mechanical Ventilators (Ventilator)
01/2021
1Duration of Therapy
01/2021
1Artificial Respiration (Mechanical Ventilation)
01/2021
1Central Venous Catheters
01/2018
1Aftercare (After-Treatment)
01/2018
1Hand Hygiene
07/2015
1Surgical Instruments (Clip)
01/2015
1Art Therapy
03/2014